ʻAlika Lipoic ʻAla (ALA)

April 20, 2021

ʻO Cofttek ka mea hana pauka Alpha Lipoic Acid (ALA) ʻoi loa ma Kina. Loaʻa i kā mākou hale hana kahi ʻōnaehana hana hoʻopihapiha piha (ISO9001 & ISO14001), me ka mana hana i kēlā me kēia mahina o 1000kg.

 


Kūlana: I ka Production Production
Mokuna: 1kg / ʻeke, 25kg / Drum

ʻO Alpha Lipoic Acid (ALA) (1077-28-7) Snāʻike

Name: ʻAlika Lipoic ʻAla (ALA)
CAS: 1077-28-7
Purity 98%
Kaulike Molecular: C8H14O2S2
Kaumaha Molecular: 206.33 g / mole
Wahi Manaʻo: 60-62 ° C (140 – 144 ° F; 333-335 K)
Inoa inoa inoa inoa: (R) -5- (1,2-Dithiolan-3-yl) waikawa pentanoic;

α-Lipoic acid; ʻAkika lipoic Alpha; Thioctic acid; 6,8-Dithiooctanoic acid

Hōʻuluʻulu Manaʻo: (±) -α-Lipoic acid, (±) -1,2-Dithiolane-3-pentanoic acid, 6,8-Dithiooctanoic acid, DL -α-Lipoic acid, DL -6,8-Thioctic acid, Lip (S2 )
InChI Key: AGBQKNBQESQNJD-UHFFFAOYSA-N
Half Ola: ʻO ka hapalua o ke ola o ka waha i haʻi ʻia ʻo ALA he 30 min wale nō
Palekana: Hoʻololi liʻiliʻi loa i ka wai (0.24 g / L); ʻO ka solubility ma ka etanol 50 mg / mL
Ke kūlana Mana: 0 - 4 C no ka wā pōkole (mau lā a i mau pule), a i ʻole -20 C no ka wā lōʻihi (mahina)
noi: Hoʻohana ʻia ka alpha-lipoic acid i loko o ke kino e wāwahi ai i nā haʻalako a hana i ka ikehu no nā mea ʻē aʻe i ke kino. Me he mea lā he antioxidant ka hana a ka Alpha-lipoic acid, ʻo ia hoʻi he pale paha i ka lolo ma lalo o nā kumu o ka ʻeha a ʻeha paha.
ʻAno: ʻO nā aniani-e like me ka nila kuʻi

 

ʻO Alpha Lipoic Acid (ALA) (1077-28-7) NMR Spectrum

 

ʻO Alpha Lipoic Acid (ALA) (1077-28-7) - NMR Spectrum

Inā makemake ʻoe iā COA, MSDS, HNMR no kēlā me kēia ʻōhua o ka huahana a me nā ʻike ʻē aʻe, e ʻoluʻolu e leka uila i kā mākou luna kūʻai kūʻai.

 

ʻO Alpha Lipoic Acid (ALA) (1077-28-7)?

ʻO ka Alpha-lipoic acid kahi hui i loaʻa kūlohelohe i loko o kēlā me kēia cell o ke kino o ke kanaka. ʻO kāna hana mua ke hoʻololi i ke kō kō (glucose) i ka ikehu e hoʻohana ana i ka oxygen, kahi hana i kapa ʻia ʻo ka aerobic metabolism. Ua manaʻo ʻia ʻo Alpha-lipoic acid kahi antioxidant, ʻo ia hoʻi hiki iā ia ke pale i nā mea hoʻoweliweli e kapa ʻia nā radical free e hoʻopōʻino i nā hunaola ma ka pae genetical.

He aha ka mea e kū hoʻokahi ai ka alpha-lipoic acid ʻo ia ka mea hiki ke hoʻoheheʻe ʻia i ka wai a me ka momona. ʻO ia ka mea hiki ke hāʻawi koke i ka ikehu a i ʻole ka hale waihona iā ia no ka wā e hiki mai ana.

Hiki i ka Alpha-lipoic acid ke hoʻohana hou i nā antioxidants "hoʻohana", e like me ka wikamina C, ka huaʻai E, a me kahi hui amino acid ikaika i ʻike ʻia ʻo glutathione.1 I nā manawa āpau e hoʻopau ai kēia mau antioxidants i kahi radical manuahi, hoʻonāwaliwali lākou a lilo i nā radical manuahi iā lākou iho. Kōkua ka alpha-lipoic acid i ka hoʻihoʻi ʻana iā lākou ma ke komo ʻana i nā electrons he nui a hoʻololi iā lākou i ka hope i kā lākou kūpaʻa.

Lawe ʻia ka waikawa Alpha-lipoic ma ke ʻano he mea kōkua ma lalo o ke kuhi hiki ke hoʻomaikaʻi i kekahi mau hana metabolic, e like me ka momona momona, hana collagen, a me ka kaohi kō glucose. Ke ulu nei nā hōʻike o ka liʻiliʻi o kekahi o kēia mau koi.

 

ʻO Alpha Lipoic Acid (ALA) (1077-28-7) keu pono

Diabetes

Ua manaʻo ʻia ua hiki i ka alpha-lipoic acid ke kōkua i ka kaohi o ka glucose ma o ka hoʻonui ʻana i ka wikiwiki i metabolized ai ke kō kō. Hiki paha i kēia ke kōkua i ka mālama ʻana i ka maʻi kō, kahi maʻi i hōʻike ʻia e nā kiʻekiʻe o ke kō glucose kiʻekiʻe.

ʻO ka loiloi ʻōnaehana 2018 a me ka meta-analysis o 20 mau hoʻokolohua hoʻokolohua kaulike ʻia o ka poʻe me nā maʻi metabolic (ʻo kekahi i loaʻa i ka maʻi maʻamau 2, ʻo kekahi poʻe i loaʻa i nā maʻi metabolic ʻē aʻe) ua hoʻoliʻiliʻi ka glucose acid i ka hoʻokēʻai ʻana, ka paʻa ʻana o ka insulin, ke kūpaʻa o ka insulin, a me ka hemoglobin o ke koko. Nā pae A1C.

 

ʻEha ʻeha

ʻO Neuropathy ka manawa olakino e hoʻohana ai e wehewehe i ka ʻeha, numbness, a me nā sensations abnormal i hoʻokumu ʻia e nā nerve nerve. ʻO ka manawa pinepine, hoʻokumu ʻia ka pōʻino e ke koʻikoʻi oxidative i kau ʻia ma nā ʻalolo e nā maʻi maʻi mau e like me ka maʻi kō, ka maʻi Lyme, nā ʻalā, nā maʻi thyroid, nā kōpaʻa ʻole, a me ka maʻi HIV.

Manaʻo ʻia e kekahi poʻe ʻo ka alpha-lipoic acid, i hāʻawi ʻia i nā kaha i lawa ka nui, hiki ke pale i kēia koʻikoʻi ma o ka hoʻoikaika ʻana i ka hana antioxidant ikaika. Ua ʻike ʻia ka hopena o kēia hopena i ka poʻe me ka maʻi diabetic neuropathy, kahi kūlana hoʻonāwaliwali i ʻike ʻia i ka poʻe me ka maʻi kōkō nui.

ʻO ka loiloi 2012 o nā noiʻi mai Nūlani i hoʻopau ai i kēlā me kēia lā 600-mg i loko o ka wai i loko o ʻekolu mau pule i hāʻawi ʻia ma loko o ʻekolu mau pule i hāʻawi ʻia ka "hoʻoliʻiliʻi nui a me ka pili pono ʻana i ka maʻi neuropathic."

E like me nā haʻawina diabetes mua, ua emi ka hopena o ka alpha-lipoic acid supplement a i ʻole hopena paha.

 

Weight Loss

ʻO ka hiki i ka Alpha-lipoic acid ke hoʻonui i ka puhi ʻana i ka calorie a hoʻonui i ka pohō kaumaha i hoʻonui ʻia e ka nui o nā gurusʻai a me nā mea hana mea hoʻohui. Me ka ʻōlelo ʻia, ke ulu nei nā hōʻike e hiki i ka alpha-lipoic acid ke hoʻohuli i ke kaumaha, ʻoiai me ke akahai.

Ua ʻike ʻia kahi loiloi 2017 o nā noiʻi mai ke Kulanui ʻo Yale i nā alpha-lipoic acid supplement, mai ka mahele lāʻau mai 300 a 1,800 mg i kēlā me kēia lā, ua kōkua i ka hōʻemi awelika o 2.8 paona i hoʻohālikelike ʻia i kahi placebo.

ʻAʻohe hui ma waena o ka alpha-lipoic supplement supplement a me ka nui o ka pohō kaumaha. Eia kekahi, ʻo ka lōʻihi o ka mālama ʻana e hoʻohuli i ka helu nui o ke kino o kekahi kanaka (BMI), akā ʻaʻole ka kaupaona maoli o ke kanaka.

ʻO ke ʻano o kēia, ʻoiai ke ʻike ʻia hiki iā ʻoe ke lilo i ka nui o ke kaupaona me ka alpha-lipoic acid, hiki ke hoʻomaikaʻi i kāu hui kino i ka hoʻololi ʻia ʻana o ka momona e nāʻiʻo wīwī.

 

Ka Cholesterol kiʻekiʻe

Ua manaʻo lōʻihi ʻia ka Alpha-lipoic acid e hoʻohuli i ka kaumaha a me ke olakino ma o ka hoʻololi ʻana i ka lipid (momona) i loko o ke koko. Hoʻopili kēia i ka hoʻonui ʻana i ka "maikaʻi" lipoprotein (HDL) kiʻekiʻe kolesterol ʻoiai e hoʻohaʻahaʻa ana i ka "maikaʻi" lipoprotein (LDL) kolesterol a me nā triglycerides. Hōʻike ka noiʻi hou ʻaʻole paha kēia.

I loko o kahi noi 2011 mai Kōlea mai, ua hāʻawi ʻia he 180 mau mākua i 1,200 a i 1,800 mg o ka alpha-lipoic acid i lilo he 21 pakeneka i ʻoi aku ka nui o ke kaupaona ma mua o ka placebo pūʻulu ma hope o 20 mau pule akā ʻaʻole i loaʻa ka hoʻomaikaʻi i ka huina kolesterol, LDL, HDL, a i ʻole triglycerides.

ʻO ka ʻoiaʻiʻo, ʻo nā kiʻekiʻena ʻoi loa o ka alpha-lipoic acid i hāʻawi ʻia e hoʻonui i ka nui o ka cholesterol a me ka LDL i nā mea hoʻopaʻa haʻawina.

 

ʻIli poino ʻia e ka lā

Makemake pinepine nā mea hana mea hoʻohanohano e kaena i kā lākou huahana pono mai nā waiwai "anti-kūnewa" o ka alpha-lipoic acid. Hōʻike ka noiʻi e loaʻa paha kahi hilinaʻi i kēia mau koi. Kuhi ʻia kahi ʻatikala loiloi he antioksant mana nui ia a ua aʻo ʻia no kāna hopena pale e kūʻē i ka hōʻino radiation.

 

ʻO Alpha Lipoic Acid (ALA) (1077-28-7) hana?

ʻO Alpha-lipoic acid a i ʻole ALA kahi hui kūlohelohe i hana ʻia i loko o ke kino. Lawelawe ia i nā hana nui i ka pae pae pūnaewele, e like me ka hana ana i ka ikehu. ʻOiai ke olakino ʻoe, hiki i ke kino ke hana i nā ALA āpau e pono ai no kēia mau kumu. ʻOiai ʻo ia ʻoiaʻiʻo, ua nui ka hoihoi i ka hoʻohana ʻana i nā mea hoʻohui ALA. Hoʻolaha nā loio o ALA i nā koi mai nā hopena maikaʻi no ka mālama ʻana i nā kūlana e like me ka maʻi kō a me ka HIV e hoʻonui ai i ka pohō kaumaha.

 

ʻO Alpha Lipoic Acid (ALA) (1077-28-7) Hoʻoponopono

ʻOiai manaʻo ʻia he palekana, ʻaʻohe alakaʻi e kuhikuhi ana i ka hoʻohana kūpono o ka alpha-lipoic acid. Kūʻai ʻia ka hapa nui o nā mea hoʻopihapiha waha i nā formulate mai 100 a 600 mg. Ma muli o ka hapa nui o nā hōʻike o kēia manawa, ua manaʻo ʻia kahi mahele lāʻau i kēlā me kēia lā o 1,800 mg e palekana i nā mākua.

Me kēlā ʻōlelo, ʻo nā mea āpau mai ke kaupaona o ke kino a me nā makahiki i ka hana ate a me ka hana o ka puʻupaʻa e hiki ke hoʻopili i ka mea palekana iā ʻoe ma ke ʻano he hoʻokahi. Ma ke ʻano he rula o ka manamana nui, kuhi hewa ma ka ʻaoʻao o ka akahele a koho mau i kahi mahele haʻahaʻa.

Hiki ke ʻike ʻia nā mea kōkua acid lipoic acid ma ka pūnaewele a ma nā hale kūʻai meaʻai olakino a me nā hale kūʻai lāʻau lapaʻau. No ka lawe nui ʻia ʻana, pono e lawe ʻia nā mea hoʻohui ma ka ʻōpū nele.

 

ʻO ka paukū Acid Alpha-lipoic no ka kuai(Kahi e kūʻai ai i ka pauma Alpha-lipoic Acid i ka nui)

ʻOliʻoli kā mākou ʻoihana i nā pilina lōʻihi e ko mākou mea kūʻai aku no ka mea ke nānā aku nei mākou i ka lawelawe o ka mea kūʻai aku a hāʻawi i nā huahana maikaʻi. Inā makemake ʻoe i kā mākou huahana, maʻalahi mākou me ka hoʻokaʻawale ʻana i nā kauoha e kūpono i kāu pono kūikawā a me ko mākou wikiwiki wikiwiki i nā kauoha e hōʻoia ʻoe e hoʻāʻo nui i kā mākou huahana i ka manawa. Hoʻomaopopo pū mākou i nā lawelawe i hoʻohui ʻia. Loaʻa mākou i nā nīnau a me ka ʻike e kākoʻo i kāu ʻoihana.

He mea hoʻolako mākou i ka paukū Alpha-lipoic Acid mea hoʻolako no nā makahiki he nui, hoʻolako mākou i nā huahana me ke kumukūʻai hoʻokūkū, a ʻo kā mākou huahana ke kiʻekiʻe kiʻekiʻe loa a me ka hoʻomaʻamaʻa ʻana i nā hoʻokolohua kūʻokoʻa e hōʻoia i ka palekana o ka ʻai ma ka honua holoʻokoʻa.

 

E hoʻomaopopo '

  1. Haenen, GRMM; Bast, A (1991). "Scavenging o hypochlorous acid e ka lipoic acid". ʻO Biochemical Pharmacology. 42 (11): 2244-6. hana: 10.1016 / 0006-2952 (91) 90363-A. PMID 1659823.
  2. Biewenga, GP; Haenen, GR; Bast, A (Kepakemapa 1997). "ʻO ka lāʻau lapaʻau o ka lāhui lipoic antioxidant". ʻOihana Pharmacology Nui. 29 (3): 315–31. hana: 10.1016 / S0306-3623 (96) 00474-0. PMID 9378235.
  3. Schupke, H; Hempel, R; Petero, G; Hermann, R; et al. (Iune 2001). "Nā ala metabolic hou o ka alpha-lipoic acid". ʻO ka lāʻau Metabolism a me ka Disposition. 29 (6): 855-62. PMID 11353754.
  4. ʻAcker, DS; Wayne, WJ (1957). "Optical ʻeleu a me radioactive α-lipoic acid". Pai o ka American Chemical Society. 79 (24): 6483-6487. hana: 10.1021 / ja01581a033.
  5. Hornberger, CS; Heitmiller, RF; Gunsalus, IC; Schnakenberg, GHF; et al. (1952). "Hoʻomākaukau synthetic o ka lipoic acid". Pai o ka American Chemical Society. 74 (9): 2382. doi: 10.1021 / ja01129a511.