Coluracetam (135463-81-9)

E 8, 2021

ʻO Cofttek ka Coluracetam ka mea hana pauka ma Kina. Loaʻa i kā mākou hale hana kahi ʻōnaehana hana hoʻopihapiha piha (ISO9001 & ISO14001), me ka mana hana i kēlā me kēia mahina o 160kg.

 


Kūlana: I ka Production Production
Mokuna: 1kg / ʻeke, 25kg / Drum

Coluracetam (135463-81-9) Snāʻike

Name: ʻO Coluracetam
CAS: 135463-81-9
Purity 98%
Kaulike Molecular: C19H23N3O3
Kaumaha Molecular: 341.411 g / moll
Wahi Manaʻo: N / A
Inoa inoa inoa inoa: N-(2,3-dimethyl-5,6,7,8-tetrahydrofuro[2,3-b]quinolin-4-yl)-2-(2-oxopyrrolidin-1-yl)acetamide

MKC-231

bci-540

Hōʻuluʻulu Manaʻo: ʻO Coluracetam; BCI-540; MKC-231; BCI 540; MKC 231; BCI540; MKC231.
InChI Key: PSPGQHXMUKWNDI-UHFFFAOYSA-N
Half Ola: N / A
Palekana: Hoʻopukaʻia ma DMSO
Ke kūlana Mana: Maloo, ʻeleʻele a ma 0 - 4 C no ka wā pōkole (mau lā a i mau pule) a -20 C no ka wā lōʻihi (mahina i mau makahiki)
noi: ʻO ka pulupāʻau puluracetam (MKC-231) he huakila racetam huakiʻia i kapaʻia e lilo i pūpū nootropic.
ʻAno: ka paʻi keʻokeʻo keʻokeʻo

 

Coluracetam (135463-81-9) NMR Spectrum

Coluracetam (135463-81-9) NMR Spectrum

Inā makemake ʻoe iā COA, MSDS, HNMR no kēlā me kēia ʻōhua o ka huahana a me nā ʻike ʻē aʻe, e ʻoluʻolu e leka uila i kā mākou luna kūʻai kūʻai.

 

He aha ʻO Coluracetam (135463-81-9)?

ʻO ka pulupāʻau puluracetam (MKC-231) he huakila racetam huakiʻia i kapaʻia e lilo i pūpū nootropic. ʻAʻole ia he hōʻike nui e nānā ana iā ia, akā, uaʻike loaʻia nāʻano hana (a me ka hoʻohālikelike) mai nā mea likeʻole e like me Piracetam a me'Aniracetam.

Hoʻopili ka pāʻali Coluracetam i ka pākaniʻana me ka hana iʻikeʻia e like me ke kūʻana o ka hilinaʻi kiʻekiʻe (HACU no ka pōkole),ʻo ia ka palena e kau palena i nā palena o ke kaha kiʻiʻana i loko o ke neuron no ka hōʻailona i loko o ka acetylcholine neurotransmitter. ʻO ka hoʻonuiʻana i ka hanana HACU e hoʻonui i ka hana o nā neuronic cholineric, no laila, he mea i makemakeʻia no ka hoʻonuiʻana i kaʻike.

 

ʻO Coluracetam (135463-81-9) maika

  • E hoʻomaikaʻi i ka hoʻomanaʻo ʻana a me ke aʻo ʻana
  • E hoʻomaikaʻi i ka hoʻomaʻamaʻa heluhelu a me nā hoʻomanaʻo ʻole
  • ʻO ka hoʻomaikaʻi lōʻihi lōʻihi
  • Hoʻēmi i ka mālama maʻi-pale kūloko
  • Hoʻolaha holomua Neurogenesis
  • Hiki ke hoʻomaikaʻi i kahi maʻi Mental
  • E hoʻomaikaʻi hoʻomaikaʻi ʻia ʻike
  • Hoʻokomo ʻia kahi hōʻailona hoʻomaikaʻi Bowel Syndrome
  • Hoʻohana hoʻohana Coluracetam

 

ʻO Coluracetam (135463-81-9) hana

ʻO Coluracetam (INN) (inoa inoa BCI-540; ʻo MKC-231 ka pauka i mua he lālā nootropic o ka ʻohana racetam. Ua hoʻomohala mua ʻia e nā Mitsubishi Tanabe Pharma Corporation no ka maʻi ʻo Alzheimer. Ma hope o ka hiki ʻole o ka lāʻau i ke kiko kikoʻī i loko o kāna mau hoʻokolohua hoʻokolohua ua laikini ʻia e BrainCells Inc no nā noiʻi ʻana i ka maʻi depressive nui (MDD), i hānai ʻia e ka "Qualifying Therapeutic Discovery Program Grant" e ka mokuʻāina ʻo Kaleponi.

 

ʻO Coluracetam (135463-81-9) Hoʻoponopono

Ua hanaʻia ka hapanui o ka noiʻiʻana ma keʻano o ka holoholona ma keʻano o nā holoholona ma mua o nā kānaka, no lailaʻaʻohe mau'ōlelo alakaʻi i laweʻia i ke ao holoʻokoʻa. Hoʻohālikelikeʻia ka laulima hana i 5-20 mg. Ua hoʻolaha nā mea hoʻohana o coluracetam i nā hanana likeʻole i lawelaweʻia ma ka'ōlelo a me ka haʻahaʻa.

Ua ʻōlelo pū nā manaʻo o ka mea hoʻohana i ka hoʻomanawanui ʻana i ka paukū coluracetam hiki ke ulu koke. E like me nā lāʻau āpau, keu hoʻi i nā nootropics, ʻoi aku ka maikaʻi o ka hoʻomaka ʻana ma nā kaha liʻiliʻi a piʻi i luna ka lāʻau i ka hopena o kou kino a hoʻomaʻa i ka lāʻau. ʻAʻohe mea ʻona ʻo Coluracetam a manaʻo ʻia he hoʻomanawanui maikaʻi a palekana.

 

ʻO ka puluracetam kalo no ka kuai(Kahi e kūʻai ai i ka paukū Coluracetam i ka nui)

ʻOliʻoli kā mākou ʻoihana i nā pilina lōʻihi e ko mākou mea kūʻai aku no ka mea ke nānā aku nei mākou i ka lawelawe o ka mea kūʻai aku a hāʻawi i nā huahana maikaʻi. Inā makemake ʻoe i kā mākou huahana, maʻalahi mākou me ka hoʻokaʻawale ʻana i nā kauoha e kūpono i kāu pono kūikawā a me ko mākou wikiwiki wikiwiki i nā kauoha e hōʻoia ʻoe e hoʻāʻo nui i kā mākou huahana i ka manawa. Hoʻomaopopo pū mākou i nā lawelawe i hoʻohui ʻia. Loaʻa mākou i nā nīnau a me ka ʻike e kākoʻo i kāu ʻoihana.

ʻO mākou kahi mea hoʻolako ʻo Coluracetam ka paukū no nā makahiki he nui, hoʻolako mākou i nā huahana me ke kumukūʻai hoʻokūkū, a ʻo kā mākou huahana ke kiʻekiʻe kiʻekiʻe a ke hana nei i nā hoʻokolohua kūʻokoʻa, kūʻokoʻa e hōʻoia i ka palekana o ka ʻai ma ka honua holoʻokoʻa.

 

E hoʻomaopopo '

[1] Akaike A, et al. (1998). Ka hopena pale o MKC-231, kahi mea hoʻonui i ka choline uptake enhancer, ma ka cytotoxicity glutamate i nā neurons cortical i hoʻolauna ʻia. Jpn J Pharmacol.

[2] Bessho, T., Takashina, K., Tabata, R., Ohshima, C., Chaki, H., Yamabe, H., Egawa, M., Tobe, A., & Saito, K. (1996). Ka hopena o ka novel affinity choline uptake enhancer 2- (2-oxopyrrolidin-1-yl) -N- (2,3-dimethyl-5,6,7,8-tetrahydrofuro [2,3-b] quinolin-4- yl) acetoamide ma nā hemahema o ka wai maze e aʻo nei i nāʻiole. Arzneimittel-Forschung, 46 (4), 369-373.

[3] Murai, S., Saito, H., Abe, E., Masuda, Y., Odashima, J., & Itoh, T. (1994). ʻO MKC-231, kahi mea hoʻonui i ka choline, hoʻonui i nā hemahema hana hoʻomanaʻo a hoʻemi ʻia ka acetylcholine hippocampal i hoʻoulu ʻia e ka ethylcholine aziridinium ion i nāʻiole. Ka Nupepa o Neural Transmission, 98 (1), 1 - 13. Doi: 10.1007 / bf01277590.

[4] Takashina K, Bessho T, Mori R, Eguchi J, Saito K. MKC-231, he mea hoʻomaikaʻi choline uptake: (2) Hoʻopilikia i ka synthesis a hoʻokuʻu i ka acetylcholine i nā kīlani lapaʻau i hana ʻia e AF64A. J Neural Transm (Wina). 2008 Jul; 115 (7): 1027-35. doi: 10.1007 / s00702-008-0048-1. PubMed PMID: 18446264.

[5] Shirayama Y, Yamamoto A, Nishimura T, Katayama S, Kawahara R. Ka hopena ma hope o ka hōʻola ʻana i ka choline uptake enhancer MKC-231 antagonizes defcyclidine-induced deficits and reduction at septal cholinergic neurons in beats. Eur Neuropsychopharmacol. 2007 Sep; 17 (9): 616-26. PubMed PMID: 17467960.