Oleoylethanolamide (OEA) (111-58-0)

Oleoylethanolamide (OEA) (111-58-0) wikiō

Oleoylethanolamide (OEA) Snāʻike

He aha ka Oleoylethanolamide (OEA) CAS 111-58-0?

ʻO Oleoylethanolamine (OEA) he mea kūloi maʻamau ka hopena o ka ethanolamide lipid a me kahi mea hoʻopiʻi kūleʻa peroxisome proliferator-activated receptor-α (PPAR-α) agonist. Hana ʻia ia i loko o ka wahī liʻiliʻi a pale i ka komo ʻana o ka meaʻai ma o ka hoʻolaʻa ʻana o PPAR-α. Hoʻohana pū ka OEA i ka GPR119, he lipid bioactive me ka hopena hypophagic a me anti-obesity.

Loaʻa ʻo Oleoylethanolamide (OEA) CAS 111-58-0

ʻO Oleoylethanolamide (OEA) kahi hana kūlohelohe i hana ʻia i loko o kou mau ʻāpana liʻiliʻi. Kōkua ʻo OEA i ka hoʻoponopono ʻana i ka pōloli, ka momona, ka momona o ke kino a me ka cholesterol ma o ka hoʻopaʻa ʻia ʻana i kahi ʻae i kapa ʻia ʻo PPAR-Alpha (Peroxisome proliferator-activated alpha alpha). I ka hana maoli, hoʻonui ka OEA i ka metabolism o ka momona o ke kino a haʻi i kou lolo ua piha ʻoe a ʻo ka manawa ke hōʻea i ka ʻai ʻana. ʻIke pū ʻia ka OEA no ka hoʻonui ʻana i nā lilo o ka calorie e pili ana me ka hana.

Oleoylethanolamide (OEA) CAS 111-58-0 Hoʻolaha i ka hana?

ʻO Oleoylethanolamide (OEA) i hoʻohuihui ʻia a hoʻoneʻe ʻia i loko o nā ʻōpū liʻiliʻi poʻo e ʻoi aku mai ka waika i loaʻa mai ka meaʻai, e like me ka ʻaila ʻoliva. Hiki i ka mea momona kiʻekiʻe ke pale aku i ka hana o ʻOEA i loko o ka wahie. Hoʻololi ka OEA i ka kōʻai ʻana o ka meaʻai ma ke kaohi ʻana i ka home oxytocin homeostatic a me ka histamine brain circuitry a me nā ala hedonic dopamine. ʻAʻohe manaʻo i hiki iā OEA ke komo i ka hedonic cannicino cannabinoid receptor 1 (CB1R) hōʻailona, ​​kahi hana e pili ana me ka nui o ka ʻaina meaʻai. Hoʻolaha ka OEA i ka lawe ʻana i nā lipid i loko o nā adipocytes e hoʻemi i ka momona momona. Ka hopena hou aku o nā hopena o ka OEA ma ka kōʻai ʻana o ka meaʻai a me ka metabolise lipid e kōkua ai i ka hoʻoholo ʻana i nā hana physiological hiki ke kuhikuhi e hoʻomohala i nā lāʻau lapaʻau hou obesity.

ʻO Oleoylethanolamide (OEA) kahi mea agonist o proliferator-hoʻālaʻa-peroxisome-hema (PPAR- α). Hoʻopau ʻo N- Oleoylethanolamide kahi hōʻailona ʻono i mea e hoʻoulu ai i ka hana dopamine waena i hoʻokumu i ka pilina ma waena o nā mana hoʻomalu caloric- homeostatic and hedonic-homeostatic. Ua hoʻokomo ʻia ʻo Oleoylethanolamide e like me ka ʻoihana molekole i pili me ka kūleʻa o ka bypass gastric. ʻO N- Oleoylethanolamide kahi mea koho koho GPR55.

Oleoylethanolamide (OEA) CAS 111-58-0 noi

Hana ʻo Oleoylethanolamide (OEA) i kahi mea i kapa ʻia ʻo PPAR a hoʻomaʻamaʻa pinepine ʻia i ka momona momona a hoʻēmi i ka mālama momona. A ʻai ʻoe, ʻai ka nui o ka OEA a emi ka momona i ka wā e pili ana nā nū sensory e pili ana i kou lolo e haʻi aku ʻoe ua piha ʻoe. ʻO PPAR-α kahi hui o ka receptor nukini ligand-activated e hoʻopili i ka hopena o ke ʻano o ka lipid metabolism a me nā kuʻuna energyhomeostasis.

Oleoylethanolamide (OEA) ka lehu no ka kuai(Ma ke kūʻai aku i ka pauka Oleoylethanolamide (OEA) ka pulupulu)

ʻOliʻoli kā mākou ʻoihana i nā pilina lōʻihi e ko mākou mea kūʻai aku no ka mea ke nānā aku nei mākou i ka lawelawe o ka mea kūʻai aku a hāʻawi i nā huahana maikaʻi. Inā makemake ʻoe i kā mākou huahana, maʻalahi mākou me ka hoʻokaʻawale ʻana i nā kauoha e kūpono i kāu pono kūikawā a me ko mākou wikiwiki wikiwiki i nā kauoha e hōʻoia ʻoe e hoʻāʻo nui i kā mākou huahana i ka manawa. Hoʻomaopopo pū mākou i nā lawelawe i hoʻohui ʻia. Loaʻa mākou i nā nīnau a me ka ʻike e kākoʻo i kāu ʻoihana.

He lāʻau ʻo Oleoylethanolamide (OEA) ka mea hoʻolako ʻenehana no nā makahiki he nui, hoʻolako mākou i nā huahana me ke kumukūʻai kūʻai, a ʻo kā mākou huahana o ke ʻano kiʻekiʻe loa a ma lalo o ka hoʻomaʻamaʻa kūʻokoʻa, kūʻokoʻa kūʻokoʻa e hōʻoia i ka palekana no ka hoʻohana ʻana a puni ka honua.

E hoʻomaopopo '

1. Gaetani S, Oveisi F, Piomelli D (2003). "Ka lihalihi ʻana o ka pāʻina ʻai i ka iole e ka anorexic lipid mediator oleoylethanolamine". Neuropsychopharmacology. 28 (7): 1311–6. doi: 10.1038 / sj.npp.1300166. PMID 12700681.
2. Lo Verme J, Gaetani S, Fu J, Oveisi F, Burton K, Piomelli D (2005). "Hoʻoponopono i ka ʻai ʻana ma ka oleoylethanolamine". Pūnaewele. Mol. Life Sci. 62 (6): 708–16. doi: 10.1007 / s00018-004-4494-0. PMID 15770421.
3. Gaetani S, Kaye WH, Cuomo V, Piomelli D (September 2008). "Ka mana o ka endocannabinoids a me kā lākou analogues i ka lesity a me ka ʻai ʻana i ka maʻi." ʻAi Hoʻohui Paʻa. 13 (3): e42–8. PMID 19011363.