ʻO Oleoylethanolamide (OEA) pauka (111-58-0)

OEA pauka (111-58-0) wikiō

Pauka OEA Snāʻike

Oleoylethanolamide (OEA) (111-58-0) NMR Spectrum

Inā makemake ʻoe iā COA, MSDS, HNMR no kēlā me kēia ʻōhua o ka huahana a me nā ʻike ʻē aʻe, e ʻoluʻolu e leka uila i kā mākou luna kūʻai kūʻai.

He aha ka Oleoylethanolamide (OEA) CAS 111-58-0?

ʻO Oleoylethanolamine (OEA) he mea kūloi maʻamau ka hopena o ka ethanolamide lipid a me kahi mea hoʻopiʻi kūleʻa peroxisome proliferator-activated receptor-α (PPAR-α) agonist. Hana ʻia ia i loko o ka wahī liʻiliʻi a pale i ka komo ʻana o ka meaʻai ma o ka hoʻolaʻa ʻana o PPAR-α. Hoʻohana pū ka OEA i ka GPR119, he lipid bioactive me ka hopena hypophagic a me anti-obesity.

Oleoylethanolamide (OEA) CAS 111-58-0 keu pono

ʻO Oleoylethanolamide (OEA) kahi hana kūlohelohe i hana ʻia i loko o kou mau ʻāpana liʻiliʻi. Kōkua ʻo OEA i ka hoʻoponopono ʻana i ka pōloli, ka momona, ka momona o ke kino a me ka cholesterol ma o ka hoʻopaʻa ʻia ʻana i kahi ʻae i kapa ʻia ʻo PPAR-Alpha (Peroxisome proliferator-activated alpha alpha). I ka hana maoli, hoʻonui ka OEA i ka metabolism o ka momona o ke kino a haʻi i kou lolo ua piha ʻoe a ʻo ka manawa ke hōʻea i ka ʻai ʻana. ʻIke pū ʻia ka OEA no ka hoʻonui ʻana i nā lilo o ka calorie e pili ana me ka hana.

Oleoylethanolamide (OEA) CAS 111-58-0 Hoʻolaha i ka hana?

Hoʻokomo ʻia a hoʻoneʻe ʻia ʻo Oleoylethanolamide (OEA) i loko o ka ʻōpū liʻiliʻi mai loko mai o ka acidic acid i loaʻa mai i ka papaʻai. Hiki i ka papaʻai momona kiʻekiʻe ke pale i ka hana OEA i loko o ka ʻōpū. Hoʻoemi ka OEA i ka lawe ʻana o ka meaʻai ma o ka hoʻoulu ʻana i ka homeostatic oxytocin a me ka histamine lolo circuitry a me nā hedonic dopamine pathways. Aia kekahi hōʻike e hiki paha i ka OEA ke hoʻouluulu i ka hedonic cannabinoid receptor 1 (CB1R) i hōʻailona, ​​ʻo ka hoʻoulu ʻia e pili pū me ka hoʻonui ʻana o ka ʻai. Hoʻoemi ka OEA i ka lawe lipid i nā adipocytes e hoʻemi i ka nui momona. ʻO ka elucidation hou aʻe o nā hopena o ka OEA i ka lawe ʻana i ka meaʻai a me ka lipid metabolism e kōkua i ka hoʻoholo ʻana i nā ʻano physiological i hiki ke hoʻopaʻa ʻia e hoʻomohala i nā hoʻoponopono momona ʻoi aku ka maikaʻi.

ʻO Oleoylethanolamide (OEA) kahi agonist o ka peroxisome proliferator-activated receptor-α (PPAR- α). Hoʻokumu ʻo N- Oleoylethanolamide i kahi ʻōpū ʻōpū e hoʻoulu ai i ka hana dopamine kikowaena e hoʻokumu ana i kahi loulou ma waena o nā mea mālama hale calistic- homeostatic a me hedonic- homeostatic. Hoʻopili ʻia ʻo Oleoylethanolamide e like me ke ʻano o ka mole molaki e pili ana i ka holomua o ka gastric. ʻO N- Oleoylethanolamide kahi agonist GPR55 wae.

Oleoylethanolamide (OEA) CAS 111-58-0 noi

Hana ʻo Oleoylethanolamide (OEA) e hoʻoulu i kahi mea i kapa ʻia ʻo PPAR a hoʻonui pū i ka momona momona a hoʻemi i ka mālama momona. Ke ʻai ʻoe, hoʻonui ka pae OEA a hoʻemi kou makemake i ka wā e haʻi ai nā aʻalolo sensory e hoʻopili i kou lolo ua piha ʻoe. ʻO PPAR-α kahi hui o ka receptor nukelika hoʻoulu ʻia e ligand i komo i loko o ka moʻo hōʻike o ka lipid metabolism a me nā ala Energyhomeostasis.

Pauka OEA no ka kuai(Kahi e kūʻai ai i ka pauka Oleoylethanolamide (OEA) i ka nui)

ʻOliʻoli kā mākou ʻoihana i nā pilina lōʻihi e ko mākou mea kūʻai aku no ka mea ke nānā aku nei mākou i ka lawelawe o ka mea kūʻai aku a hāʻawi i nā huahana maikaʻi. Inā makemake ʻoe i kā mākou huahana, maʻalahi mākou me ka hoʻokaʻawale ʻana i nā kauoha e kūpono i kāu pono kūikawā a me ko mākou wikiwiki wikiwiki i nā kauoha e hōʻoia ʻoe e hoʻāʻo nui i kā mākou huahana i ka manawa. Hoʻomaopopo pū mākou i nā lawelawe i hoʻohui ʻia. Loaʻa mākou i nā nīnau a me ka ʻike e kākoʻo i kāu ʻoihana.

He mea hoʻolako mākou i ka pauka Oleoylethanolamide (OEA) no nā makahiki he nui, hoʻolako mākou i nā huahana me ke kumu kūʻai hoʻokūkū, a ʻo kā mākou huahana ke kiʻekiʻe kiʻekiʻe loa a ke hana nei i nā hoʻokolohua koʻikoʻi, kūʻokoʻa e hōʻoia i ka palekana o ka ʻai ma ka honua holoʻokoʻa.

E hoʻomaopopo '

1. Gaetani S, Oveisi F, Piomelli D (2003). "Hoʻohālikelike i ka papa ʻaina i ka ʻiole e ka mediator lipid anorexic oleoylethanolamine". Neuropsychopharmacology. 28 (7): 1311-6. hana: 10.1038 / sj.npp.1300166. PMID 12700681.
2. ʻO Lo Verme J, Gaetani S, Fu J, Oveisi F, Burton K, Piomelli D (2005). "Ka hoʻoponopono ʻana i ka lawe ʻana i ka meaʻai e oleoylethanolamine". Pūnaewele. Mol. ʻO Life Sci. 62 (6): 708-16. hana: 10.1007 / s00018-004-4494-0. PMID 15770421.
3. Gaetani S, Kaye WH, Cuomo V, Piomelli D (Kepakemapa 2008). "Ke kuleana o endocannabinoids a me kā lākou analogues i ka momona a me nā maʻi ʻai". ʻAi i ke Kaumaha Paona. 13 (3): e42-8. PMID 19011363.

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