Ma hope o ka 2019-hoʻopaʻa hopena ua ʻO Nicotinamide Mononucleotide palekana no ka ʻai kanaka inā palena ʻia kāna ʻai i ka palena i kuhikuhi ʻia, ua komo kekahi mau ʻoihana hana i ka mākeke me kā lākou mōhai. ʻO kēia overabundance o ke koho i waiho huikau nā mea kūʻai mai e pili ana i ka mea Hoʻohui ʻia Nictonimade Mononucleotide (NMN) ʻoi aku ka maikaʻi no lākou. I ko mākou manaʻo, ʻo ka mea hoʻohui anti-kūnewa ʻoi loa o Nicotinamide Mononucleotide (NMN) i ka makahiki 2021 ʻo ia ka hui Cofttek.
ʻO Cofttek kahi hui A + i helu ʻia ma ka mākeke no kahi o 12 mau makahiki a ua hoʻomohala i kahi kumu ukali pono ma kēia manawa. ʻO ka pauma NMN i hoʻolako ʻia e ka ʻoihana he ʻekolu hoʻokolohua hoʻokolohua, NMN papa lāʻau lapaʻau i lawe ʻia mai nā hui like i hoʻolako ʻia i ka NMN no nā hoʻokolohua olakino koʻikoʻi kanaka i hana ʻia i loko o nā makahiki. ʻO ka Paukū NMN hoʻolako ʻia e Cofttek e hoʻoikaika i kona maʻalahi o ka komo ʻana i loko o ke kino, e hoʻonui ai i ka bioavailability o ka huahana a me kāna hana physiological. ʻOi aku ka mea nui, hele mai kēia lōkihi me bulk a hiki iā ʻoe ke mālama no ia i ʻekolu mahina. ʻO nā mea āpau a pau, ʻo kēia kekahi o nā mea hoʻohui maikaʻi loa i loaʻa i kēia manawa i ka mākeke me ka helu ʻana o nā mea hoʻohana kiʻekiʻe a hiki mai ia mai kahi hui i hoʻopakele i nā huahana ʻoiaʻiʻo a maikaʻi hoʻi i kēlā me kēia makahiki.

He aha ka Nicotinamide Mononucleotide (NMN)?

ʻO Nicotinamide Mononucleotide (1094-61-7) a i ʻole NMN kahi nukelea i kū kūlohelohe i loko o ka hapa nui o nā meaʻai a mākou e ʻai ai. ʻIke ʻia i ka avocado, broccoli, kukama, kāpiki, edamame, a me nā ʻōmato. Eia nō naʻe, ʻaʻole lawa ka nui o ka NMN i hoʻolako ʻia e kēia mau meaʻai i mea e hoʻomau ai i nā hana kino nui a no laila, ʻōlelo pinepine ʻia ka poʻe e lawe i nā mea hoʻopihapiha NMN. Akā, no ke aha he mea nui a NMN no ke kino?

ʻO Nicotinamide Mononucleotide a i ʻole NMN kahi mea mua o Nicotinamide Adenine Dinucleotide a i ʻole NAD +. I nā huaʻōlelo maʻalahi, ʻo NMN ka mea hoʻohui i hoʻohuli ʻia i NAD + ma o ke kaʻina o nā hopena kemika i kū i loko o nā hunaola. ʻO NAD +, ma ka ʻaoʻao ʻē aʻe, manaʻo ʻia he mea nui ia no ke kino ʻoiai e hana ana i nā hana nui, e like me ke kaulike ʻana i ke kaʻina o ka circadian o ke kino, e wāwahi ana i nā meaola e hoʻokuʻu ai i ka ikehu cellular, a me ka hoʻoikaika ʻana i nā hopena enzymatic kī, ʻo kekahi o lākou e hoʻopaneʻe i ka ʻelemakule. Minamina, ʻoiai loaʻa ʻo NAD + i loko o kēlā me kēia keena o ke kino, hoʻemi ka hana me ka makahiki. ʻO ka mea nui aku, ʻaʻohe meaʻai e hiki i ke kanaka ke hoʻopau e hoʻonui i ka hana o NAD + i loko o ke kino. No laila, koi ke kino i kahi NAD + precursor e hoʻololi i loko o NAD + i loko o ka cell, no laila ke kaulike ʻana i kona iho i loko o ke kino. ʻO kēia kahi e pāʻani ai ka hoʻohana ʻana o nā mea hoʻopihapiha NMN.

(1)↗

Punawai Haumana

PubMed Central

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No ke aha Nmn maikaʻi?

Ua loaʻa ʻo NMN e hoʻomaikaʻi i ka hana a me ka hana ʻana o ka insulin, e hopena ana i nā keu pono metabolabolic a me ka hoʻomanawanui ʻana o ka glucose. I ke kikoʻī, hiki i nā mea hoʻopihapiha NMN ke kōkua i ka hana e hōʻemi i nā kūlana metabolic e like me ka maʻi diabetes, ka maʻi momona o ka ate, a me ka momona.

Hiki iā Nmn ke hoʻohuli i ka ʻelemakule?

Ka hoʻoponopono ʻana o nikotinamide mononucleotide (NMN) Ua hōʻike ʻia e hoʻoliʻiliʻi i nā hana e pili ana i ka ʻelemakule. Hoʻonui ka Nototinamide mononucleotide (NMN) i ka hōʻike anti-ʻelemakule miRNA hōʻike i ka aorta o nā ʻiole ʻelemakule, e wānana nei i ka epigenetic rejuvenation a me anti-atherogenic effects.

Pehea ʻoe e hoʻonui ai iā Nmn kūlohelohe?

Hiki ke hāʻawi palekana ʻia ʻo NMN i nāʻiole a ʻike kūlohelohe ʻia i nā ʻano meaʻai like ʻole, e like me broccoli, kāpiki, kukama, edamame a me ka avocado. Hōʻike ka noiʻi hou i ka wā e hemo ai ka NMN i ka wai inu a hāʻawi ʻia i nāʻiole, ʻike ʻia i ke kahe o ke koko ma lalo o ʻekolu mau minuke.

Hiki iā Nmn ke hoʻonui i ka lōʻihi?

Ua aʻo nā ʻepekema i ʻelua mau waena waena, nicotinamide riboside (NR) a me ka monotucleamide nicotinamide (NMN), ʻoi aku ka nui ma mua o nā mea ʻē aʻe, a he mea hōʻoluʻolu ka noiʻi. Hōʻike kekahi mau noiʻi e hoʻopili ana me kēia mau mea mua i hiki ke hoʻonui i nā pae NAD + a hoʻolōʻihi i ke ola o ka hū, nā ilo, a me nāʻiole.

Pehea ka lōʻihi o ka noho ʻana o Nmn i kāu ʻōnaehana?

Ke hōʻike maopopo nei kā mākou noi o kēia manawa e lawe koke ʻia ʻo NMN mai ka ʻōpū i loko o ke kahe o ke koko ma waena o 2-3 min a hoʻomaʻemaʻe ʻia hoʻi mai ke kahe o ke koko i loko o nā pūnaewele i loko o 15 min.

(2)↗

Punawai Haumana

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He aha ka hana ke pau kou lawe ʻana iā Nmn?

Hana nā Resveratol a me NMN ma ka hoʻomaikaʻi ʻana i ka hiki o nā hunaola i kou kino e hoʻoponopono iā lākou iho. No laila, inā lawe ʻoe iā lākou no kekahi manawa a laila hoʻokū ʻaʻole ia e kumu iā ʻoe e hoʻi koke i ka mokuʻāina āu i noho ai ma mua o ka lawe ʻana iā lākou no ka mea he hoʻomaikaʻi maoli nā loli i ka hana o ka cell.

Hana ʻoe iā Nmn e ʻōpio?

"Ua hōʻike ko mākou keʻena hoʻokolohua i ka hāʻawi ʻana i ka NMN i nāʻiole ma mua o 12 mau mahina e hōʻike nei i nā hopena kūʻē kūnewa." Wahi a Imai, ʻo ka unuhi ʻana i nā hopena i nā kānaka e hōʻike ana hiki i ka NMN ke hāʻawi i kahi kanaka me ka metabolism o 10 a 20 mau makahiki i ʻōpio.

He aha ke kumukanawai maikaʻi loa no ka ʻelemakule ʻili?

ʻO ka 12 Mea Kūʻai Kūpono Kūpono Loa

  • Curcumin
  • EGCG
  • ʻO Collagen
  • CoQ10
  • ʻO Nicotinamide riboside a me ka nicotinamide mononucleotide
  • ʻO Crocin
  • ʻO Theanine
  • Rhodiola
  • Kāleka
  • Astragalus
  • Ka uku iʻa
  • Resveratrol

Pehea e hiki ai iaʻu ke hoʻohuli kūlohelohe i nā wrinkle?

  • E hoʻohana i ka pale māmā.
  • Palena i ka lawe kō.
  • E haʻalele i ka puhi pua ʻana.
  • E hoʻohana i ka aila niu.
  • Lawe i ka beta carotene.
  • E inu i ka tī lau lemon.
  • Hoʻololi i ke kūlana hiamoe.
  • E holoi i kou helehelena.
  • Hōʻalo i nā kukui ultraviolet
  • E piʻi i kāu mau antioxidant

Pehea e hiki ai iaʻu ke hoʻohuli i ka ʻelemakule?

I mea e kōkua ai i ko lākou poʻe maʻi e pale i ka ʻelemakule o ka ʻili, hāʻawi nā dermatologists i kā lākou mau maʻi i nā ʻōlelo aʻoaʻo aʻe.

  • Palekana i kou ʻili mai ka lā i kēlā me kēia lā.
  • E noi iā ia iho ma kahi o ka ʻili.
  • Inā puhi ʻoe, kū.
  • Hōʻalo i nā helehelena hou.
  • ʻAi i kahi papaʻai olakino, kaulike maikaʻi.
  • E inu liʻiliʻi i ka waiʻona.
  • Hoʻomaʻamaʻa i nā lā he nui o ka pule.
  • E hoʻomaʻemaʻe i kou ʻili me ka mālie.
  • E holoi i kou alo i ʻelua mau manawa i ka lā a ma hope o ka hou nui ʻana i ka hou.
  • Hoʻoki i ka hoʻohana ʻana i nā huahana mālama ʻili e ʻeha a wela paha.

He aha ka ʻōlelo a Sinclair?

Lawe ʻo David Sinclair:

Resveratrol - 1g / i kēlā me kēia lā - i ke kakahiaka me ka yogurt (ʻike i kahi e kūʻai ai) Nicotinamide Mononucleotide (NMN) - 1g / i kēlā me kēia lā - kakahiaka (e ʻike i kahi e kūʻai ai) Metformin (lāʻau lapaʻau) - 1g / i kēlā me kēia lā - 0.5g i ke kakahiaka & 0.5g i ka pō - koe wale nā ​​lā ke hoʻoikaika.

Loaʻa nā hopena ʻē aʻe iā Nmn?

Ke lawe ʻia e ka waha: SAOTE POSSIBLY SAFE ʻo Nicotinamide riboside ke hoʻohana ʻia ka wā pōkole. ʻO nā hopena ʻaoʻao o ka nicotinamide riboside he maʻa mau. Hiki i nā hopena ʻē aʻe ke komo pū me nā pilikia o ka ʻōpū e like me ka nausea a me ka bloating a i ʻole nā ​​pilikia o ka ʻili e like me ka ʻume ʻana a me ka hou nui ʻana.

(3)↗

Punawai Haumana

PubMed Central

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E hele i ke kumu

He aha nā hopena ʻē aʻe o resveratrol?

Ke lawe ʻia e ka waha: Resveratrol is LIKELY SAFE ke hoʻohana ʻia i nā nui i loaʻa i nā meaʻai. Ke lawe ʻia i nā kaha a i ka 1500 mg i kēlā me kēia lā a hiki i 3 mau mahina, POSSIBLY SAFE ka resveratrol. Hoʻohana palekana ʻia nā kiʻekiʻena kiʻekiʻe a hiki i 2000-3000 mg i kēlā me kēia lā no 2-6 mau mahina. Eia nō naʻe, ʻoi aku ka nui o kēia mau lāʻau kiʻekiʻe o resveratrol i nā pilikia o ka ʻōpū.

Mālama ʻia ka nicotinamide i kēlā me kēia lā?

Maluhia paha ʻo Nicotinamide riboside me ka liʻiliʻi - inā loaʻa - nā hopena ʻaoʻao. I nā noiʻi kanaka, ʻo ka lawe ʻana i ka 1,000-2,000 mg i kēlā me kēia lā ʻaʻole i loaʻa nā hopena ʻino. Eia nō naʻe, pōkole ka hapanui o nā noiʻi kanaka a he kakaikahi wale nā ​​mea komo. No kahi manaʻo pololei o kona palekana, pono i nā noiʻi kanaka hou aku i koi ʻia.

No ke aha i hewa ai ka NADH nui loa?

Hiki i kēia NADH keu ke haki i ke kaulike redox ma waena o NADH a me NAD +, a hiki i ka hopena ke alakaʻi i ka stress oxidative a me nā ʻano like ʻole o nā synabome metabolic.

ʻO wai ka ʻoi aku ʻo Nmn a ʻo NR paha?

Manaʻo pinepine ʻia ʻo NR ma ke ʻano he mākaukau mua loa i ka NAD +, akā ʻo kona hoahānau ka mole mole NMN, ʻoiai ʻaʻole ia he mea hana ma Basis, ke hāpai nei i nā kuʻemaka e like me ke keiki hou ma ka palaka.

ʻOi aku ka nui o ka NMN ma mua o ka NR, ʻo ia hoʻi he pono e wāwahi pinepine ʻia e komo i loko o ka pūnaewele. NR, ke hoʻohālikelike ʻia i nā mea mua o NAD + (e like me ka waikawa nikotinic a i ʻole nicotinamide) e noho aliʻi ana ma ka pono loa. Akā e hāʻawi iā NMN i kahi puka hou, kahi hiki iā ia ke komo i loko, a he pāʻani hou loa ia.

He aha ka mea kōkua Nmn ʻoi loa?

  • ʻO ka mea kōkua Nmn ʻoi aku ka maikaʻi?
  • NMN Sublingual Papa
  • NAD + Gula Liposomal NMN.
  • Nā paukū NMN.

Hoʻohuli ʻo Nmn i ka ʻelemakule?

ʻO nā ala e koi ai i ka hoʻonui ʻana o nā pae NAD + i hōʻike ʻia e hoʻomaikaʻi i ka hana mitochondrial i nā holoholona kahiko, e hoʻohuli i kekahi o nā poho i kū me ka makahiki. Ua hōʻike ʻia ka lawelawe ʻana o monotucleamide nicotinamide (NMN) e hoʻoliʻiliʻi i nā hana e pili ana i ka ʻelemakule.

Ehia mau NMN āu e lawe ai?

ʻOiai ua hoʻopaʻa ʻia nā noiʻi e palekana ana ʻo Nicotinamide Mononucleotide a i ʻole NMN no ka hoʻohana kanaka, ke hoʻomau ʻia nei ka noiʻi ʻana e ʻike ai i ka mahele lāʻau kūpono a me ke alapine o ka NMN i nā kānaka. Eia nō naʻe, ua hoʻokumu ʻia nā noiʻi ʻana i mālama ʻia a hiki i kahi 500 mg i kēlā me kēia lā ke palekana no nā kāne. I kēia mau lā, loaʻa ʻo Nicotinamide Mononucleotide i nā ʻano like ʻole, e like me nā pila a me ka pauka. Wahi a nā mea hoʻopihapiha NMN i ke kūpono o ka hoʻopili ʻana i ka waha i ka hoʻonui ʻana i ka hana NAD + i loko o ke kino. Hoʻokumu ʻia kēia mau koi i ka ʻoiaʻiʻo Slc12a8, kahi lawe lawe nicotinamide nucleotide, kōkua me ka omo ʻana o NMN i ka ʻōpū.

(4)↗

Punawai Haumana

PubMed Central

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E hele i ke kumu

Ua like Nmn me b3?

ʻAʻole ʻo NMN. ʻAʻole kahi ʻano NMN o ka huaʻai B3, a ʻaʻohe hoʻokolohua hoʻokolohua e hōʻoia e hoʻonui ana i ka NAD i nā kānaka. ʻAʻole ʻo NMN ke ʻano o ka moleola e manaʻo ʻia he huaora no ka mea aia ka phosphate, e pili ana i kona hiki ke komo i nā pūnaewele.

He aha nā meaʻai e loaʻa ai ka manaʻo kiʻekiʻe o NAD +?

Nā meaʻai e hoʻonui ai i nā pae NAD

Aia kekahi mau meaʻai i hiki ke hoʻonui i nā pae NAD i ke kino. Aia kekahi o lākou i:

  • Milk Milk - ua hōʻike ka noiʻi he wai maikaʻi maikaʻi ka waiū o ka bipi o Riboside Nicotinamide (RN). Loaʻa i kahi lita o ka waiū bipi hou ma kahi o 3.9µmol o NAD +. No laila ʻoiai ʻoe e leʻaleʻa nei i kahi kīʻaha waiū hōʻoluʻolu, ke hele ʻōpio a ʻoi aku kou olakino.
  • Iʻa - eia kekahi kumu no kou leʻaleʻa i ka iʻa! ʻo kekahi mau ʻano iʻa e like me ke tuna, nā salmona a me nā sardine he waiwai nui nā NAD + no ke kino.
  • Nūhū - makemake nā poʻe he nui i nā momona a me lākou ma ke ʻano he meaʻai maʻamau i kā lākou papaʻai maʻamau. Akā, ua ʻike anei ʻoe i nā pūlehu, ʻo ia hoʻi nā hua chimini, kōkua pū kekahi i ka hoʻonui maoli ʻana i nā pae NAD? ʻAe, pololei kēlā. No laila, ʻoluʻolu i ka ʻai ʻana i nā huaalelo a hoʻomau i ka nānā a ʻōpio a ʻoi aku ka ʻōpio.
  • Hū - he hū kahi mea hoʻohana no ka hana ʻana i ka berena a me nā huahana bakery ʻē aʻe. Aia i ka hū ʻo Riboside Nicotinamide (RN), kahi mea mua o NAD. Eia kekahi kumu ʻē aʻe e ʻoliʻoli ai i nā pāʻina punahele a i nā pōpō ke hele ʻoe i ka hale bakery! E hauʻoli i kāu meaʻai punahele ʻoiai e hoʻonui ana i nā pae NAD i ka manawa like. Pehea kēlā!
  • ʻO nā mea kanu ʻōmaʻomaʻo - nā hua ʻōmaʻomaʻo i nā ʻano huaola āpau i loko o lākou e pono ai i nā ʻano like ʻole. I kēia mau lā, ua hele mai i ka malamalama i nā mea kanu uliuli kekahi kumu maikaʻi o ka NAD no ke kino. ʻO kekahi o kēia mau huaʻai e komo pū me ka pī a me ka asparagus.
  • Nā huaʻai holoʻokoʻa - e like me ke kūkākūkā ma mua, ʻo ka Vitamin B3 kekahi me RN, ka mea mua o ka NAD. Eia nō naʻe, ke kuke ʻia a hana ʻia paha nā mea kanu, nā mea ʻai a i ʻole nā ​​mea kanu, nalowale lākou i kā lākou meaʻai pono a me ke kumuwaiwai. No laila, pono ʻoe e ʻai pū i nā lau maka a lawe i nā kīʻaha holoʻokoʻa ma kahi o nā meaʻai i hoʻoponopono ʻia.
  • E ʻokiʻoki i nā mea inu ʻona - Na NAD ke kuleana no ka mālama ʻana i nā hana metabolic holoʻokoʻa o ke kino. Hoʻopilikia ka waiʻona i kēia mau kaʻina hana a hoʻemi i ka pono o NAD. No laila, pono ʻoe e hōʻalo i ka lawe nui ʻana i nā mea inu ʻona no ka mea ʻaʻole maikaʻi ia no kou olakino.

Hana Nmn i ka flush?

ʻO ka 'Niacin flush' kahi hopena o ka lawe ʻana i nā kaha kiʻekiʻe o ka niacin supplement (Wikamina B3). Hana ka flush ke hana ka niacin i nā capillaries liʻiliʻi i kou ʻili e pālahalaha, kahi e hoʻonui ai i ke kahe o ke koko i ka ʻili o ka ʻili. ʻAʻole like me nā huakino B3 (niacin), pono ʻole ka nicotinamide riboside e hoʻoulu i ka helehelena.

Ma hea e hiki ai iaʻu ke kūʻai iā Nmn ma Kanada?

ʻO NMN kahi nucleotide i loaʻa mai i ka ribose a me ka nicotinamide. E like me ka nicotinamide riboside (Niagen), he mea loaʻa ka NMN o ka niacin, a he mea mua i ka NAD +. NMN Kanada: ʻAʻole kūʻai ʻia ʻo Nicotinamide mononucleotide i kēia manawa no ke kūʻai ʻana ma ke ʻano he papaʻai meaʻai ma Kanada.

ʻO NMN kahi nucleotide i loaʻa mai i ka ribose a me ka nicotinamide. E like me ka nicotinamide riboside (Niagen), he mea loaʻa ka NMN o ka niacin, a he mea mua i ka NAD +. NMN Kanada: ʻAʻole kūʻai ʻia ʻo Nicotinamide mononucleotide i kēia manawa no ke kūʻai ʻana ma ke ʻano he papaʻai meaʻai ma Kanada.

(5)↗

Punawai Haumana

PubMed Central

Ua mahalo nui ʻia mai ka National Institutes of Health
E hele i ke kumu

Maluhia ʻo Nmn?

I loko o nā makahiki, ua mālama ʻia kekahi mau noiʻi e hoʻopaʻa inā he palekana ʻo NMN i nā kānaka ʻaʻole paha. Ua hōʻike pinepine kēia mau noiʻi ʻana i kēlā me kēia manawa, ua palekana ʻo Nicotinamide Mononucleotide i ka hoʻohana ʻia ʻana ke kapu ʻia kona ana. Ma ka laulā, ua ʻōlelo ʻia nā kāne e pili pono i ka mahele lāʻau o kēlā me kēia lā ma lalo o 500 mg. Eia nō naʻe, pono e hoʻomālamalama ʻaʻole i ʻae ʻia e ka FDA ka NMN ma ke ʻano he lāʻau palekana. No laila, inā he maʻi āpau a i ʻole nā ​​pilikia olakino, ʻoi aku ka maikaʻi e nīnau aku ʻoe me kāu kauka ma mua o ka hoʻomaka ʻana i nā mea hoʻohui NMN.

ʻO wai ka mea ʻoi aku ka NAD a i ʻole ka NMN?

ʻO NAD a me NMN nā mea hoʻohui anti-kūnewa i makemake nui ʻia, a no ke kumu kūpono.

Pehea e hoʻonui ai i kaʻu NAD + kūlohelohe?

Hoʻonui maoli i nā pae NAD

  • Kūʻai
  • Nā Nicotinamide Riboside Mea Hoʻohui Meaʻai
  • hoʻokō '
  • Maikaʻi ʻole ka Lā ʻana o ka Lā!
  • Nā meaʻai e hoʻonui ai i nā pae NAD

He aha kaʻu e lawe ai me NMN?

I mea e hoʻomaikaʻi ai i kāu pae NAD +, hiki iā ʻoe ke lawe i nā capsule NMN i hoʻopaneʻe ʻia me kahi Sirtuin Activator e like me Resveratrol me kahi yogurt momona momona e kōkua ai i ka bioavailability o Resveratrol.

E lawe paha wau iā TMG me NMN?

Inā ʻoe e lawe nei iā NMN a i ʻole e noʻonoʻo e pili ana i ka hoʻomaka ʻana, e noʻonoʻo e hoʻohui me TMG ma ke ʻano he kākoʻo hoʻohui no ka methylation. ʻO nā mea hāʻawi methyl ʻē aʻe i kūpono e pili ana i ka methylated B6, B12, a me ka folate.

He aha ka ʻokoʻa ma waena o nicotinamide a me nicotinamide riboside? (3)

ʻO Niacin kahi ʻano oxidated o nikotine i hiki i ke kino ke hoʻolilo i NAD. ʻO Nicotinamide kahi amide o ka niacin e like me ka NAD a he hapa kona mau hopena. ʻO Nicotinamide riboside kahi ʻano synthetic o ka nikotinamide i loaʻa nā ʻano ʻokoʻa.

(6)↗

Punawai Haumana

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He niacin ʻo Nmn?

E like me ka nicotinamide riboside, he mea loaʻa ka NMN o ka niacin, a he kanaka nā ʻenema i hiki i nā kānaka ke hoʻohana i ka NMN e hana i ka nicotinamide adenine dinucleotide (NADH). I nāʻiole, komo ʻo NMN i nā pūnaewele ma o nā ʻōpū liʻiliʻi ma waena o 10 mau minuke e hoʻohuli ana iā NAD + ma o ka Slc12a8 NMN transporter.

E hoʻoliʻiliʻi ka nicotinamide riboside iā BP?

ʻO Nicotinamide riboside kahi mea kūlohelohe maoli o ka nicotinamide adenine dinucleotide (NAD +), kahi mea uwila koʻikoʻi o nā hopena maikaʻi o ka palena ʻana o ka caloric, a no laila kahi mimic calric restriction mimetic compound. Ua hoʻopau mākou i ke aʻo pailaka mua o ka nicotinamide riboside supplementation i ke olakino waena a me nā mākua makua a hōʻike i 6 mau pule o ka hoʻoliʻiliʻi ua hoʻemi ʻia ke kaomi systolic (SBP) e 8 mmHg i kēlā me kēia me ka SBP baseline o 120-139 mmHg (kiʻekiʻe SBP / pae 1 hypertension) hoʻohālikelike ʻia me placebo, a hoʻohaʻahaʻa ʻia i ka ʻāpana arterial, kahi wānana kūʻokoʻa kūʻokoʻa o CVD a me nā maʻi e pili ana a me ka make.

Aia ma hea ka betaine?

ʻIke ʻia ʻo Betaine i nā microorganism, nā mea kanu, a me nā holoholona a he mea nui ia o nā meaʻai he nui, e like me ka palaoa, ka ʻāpala, ka milo, a me nā beets kō. ʻO Betaine kahi zwitterionic quaternary ammonium compound i ʻike ʻia ʻo trimethylglycine, glycine betaine, lycine, a me oxyneurine.

(7)↗

Punawai Haumana

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He aha nā meaʻai e ho'ōki ai i nā wrinkle?

Eia nā 10 o nā meaʻai anti-kūnewa ʻoi loa e hānai i kou kino no kahi ʻālohilohi mai loko mai.

  • Kaulike
  • ʻO ka pepa ʻulaʻula ʻulaʻula
  • Papaya
  • Blueberries
  • Broccoli
  • Spinach
  • kukui
  • ʻO kaʻuala
  • Nā hua pomeraite

Pehea e hiki ai iaʻu ke nānā aku i 10 mau makahiki ʻōpio?

  • E hoʻohana i kahi mask Mask Hydrating.
  • Koho i kahi Luminous Foundation
  • E hoʻomāmā iki i kou lauoho
  • E komo i kahi Ponytail
  • Exfoliate (akā, mai hoʻonui nui)
  • Keʻokeʻo i Kou Waterline
  • Hoʻopau i kāu nānā me kahi mist Mineral

Pehea e hiki ai iaʻu ke hōʻoki i koʻu alo mai ka ʻelemakule?

  • Palekana i kou ʻili mai ka lā i kēlā me kēia lā
  • E noi iā ia iho ma kahi o ka ʻili
  • Inā puhi ʻoe, kū
  • Hōʻalo i nā helehelena hou
  • ʻAi i kahi papaʻai olakino, kaulike maikaʻi
  • E inu liʻiliʻi i ka waiʻona
  • Hoʻomaʻamaʻa i nā lā he nui o ka pule
  • E hoʻomaʻemaʻe i kou ʻili me ka mālie

ʻO nā meaʻai hea e wikiwiki ai i kou makahiki?

  1. ʻO nā ʻuala ʻuala no nā wīwī french
  2. Palaoa Sprouted no ka berena keʻokeʻo
  3. ʻO ka meli a hua paha no ke kō kō
  4. ʻO ka aila ʻoliva a i ʻole nā ​​avocados no margarine
  5. E hoʻopili me nā moa no nā meaʻai i hana ʻia
  6. Manaʻo i ka waiū
  7. E noʻonoʻo palua e pili ana i ka soda a me ke kope
  8. E inu i ka waiʻona i ke kaulike
  9. Hōʻalo i ka kuke ʻana i ka wela nui
  10. E kuapo i nā palaoa laiki
  11. Pākuʻi fructose me ka lipoic acid

He aha ka wikamina e maikaʻi no nā maka o ka maka?

Hiki i ka Vitamin C ke kōkua i ka pale aku i nā hōʻailona o ka ʻelemakule ma muli o ka hana nui i ka synthes collagen maoli o ke kino. Kōkua ia i ka hoʻōla ʻana i ka ʻili i hōʻino ʻia a, i kekahi mau hihia, hoʻoliʻiliʻi i ke ʻano o nā wrinkle. Hiki i ka lawa ʻana o ka wikamina C ke kōkua i ka hoʻoponopono a pale ʻana i ka ʻili maloʻo.

(8)↗

Punawai Haumana

PubMed Central

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No ke aha mākou e pono ai iā Nicotinamide Mononucleotide (NMN)?

Pili ka manawa i ka manawa a me ka manawa i kōkua ʻia i ka retrogression o ka hana kino kanaka. ʻOiai ʻaʻole hiki ke pale ʻia ka ʻelemakule a hiki ʻole ke hōʻalo ʻia, ua hoʻolilo nā ʻepekema i mau makahiki i ka hoʻomaopopo ʻana pehea e lohi ai a kāohi ʻia ai kēia kaʻina hana. Ua alakaʻi ʻia kēia noiʻi hoʻomau i ka loaʻa ʻana o kekahi mau mea a me nā mea hoʻohui me nā waiwai anti-ʻelemakule i hiki ke hoʻolilo ʻia i mea hoʻohui anti-ʻelemakule. ʻO kekahi ʻano hui pū me nā waiwai anti-kūnewa nui a ka poʻe ʻepekema e manaʻo nui nei ʻo NMN a ʻo Nicotinamide Mononucleotide paha. Ma kēia ʻatikala, kūkākūkā mākou i nā mea āpau e ʻike e pili ana i ka NMN a me ka hoʻopiha anti-ʻelemakule maikaʻi loa o nicotinamide mononucleotide ma 2022.

Hoʻohana ʻo Nicotinamide Mononucleotide (NMN)

Ma mua o kekahi mau makahiki i hala aku nei, ua hana ʻia nā noiʻi āpau e pili ana i ka hoʻohana ʻana o NMN i nā holoholona a ʻoiai ke hōʻike nei kēia mau noiʻi i nā hopena kūleʻa, ʻaʻole lawa kēia mau hopena e hoʻokumu i nā maikaʻi o ka NMN hoʻohana i nā kānaka. I ka 2016, ua mālama ʻia kahi noiʻi e kālailai i ka palekana o ka hoʻohana ʻana o NMN a me kāna papa manawa i ke koko kanaka. Ua hāʻawi ka noiʻi i nā hopena i hoʻohiki ʻia. Kau ʻia, ua mālama ʻia kahi noiʻi ʻē aʻe i ka makahiki 2016 e hoʻopaʻa i ka hopena o ka ʻai ʻana o NMN i 50 mau wahine makua e loaʻa ana i ka BMI kiʻekiʻe, ka glucose koko, a me nā triglyceride koko. Ua kūleʻa ke aʻo ʻana. Eia nō naʻe, no ka mea, ua kapu ʻia ka papa noiʻi i nā wahine o kekahi mau makahiki, ua manaʻo ka poʻe ʻepekema he nui nā hōʻoia e pono ai no ka mālama ʻana inā palekana ʻo NMN no nā kānaka.

No laila, ʻoi aku ka mea hou loa ma 2019, ua hana ʻia kahi haʻawina ma ka Unit Clinical Trial Unit o ke Kula University University of Medicine. ʻO ke kumuhana o ka aʻo ʻana he 10 mau kāne ma waena o 40 a 60. Ua mālama ʻia kēia mau kāne me nā ʻōhua mai 100 mg a 500 mg. Ua pau ka hōʻike ʻana i kā NMN ka maikaʻi loa o ke kanaka a he palekana ka hoʻopau ʻana a pau ke hoʻoponopono ʻia i kona hoʻohana ʻana. He mea koʻikoʻi kēia haʻawina ʻo ia ka noiʻi NMN mua i hana ai i nā kānaka e aʻo i ka hopena o NMN i ka ola kino o ke kanaka. I ka hana kūpono ʻana ua palekana ka make o NMN, hoʻomaka nā mea hana i ke kīleʻaleʻa me ka lako me nā lako NMN, i lilo i mea maʻamau i kēia mau lā.

maika

Ma kēia ʻāpana, kūkākūkā mākou i nā pono kūpono i hoʻopili ʻia me Nicotinamide Mononucleotide a i ʻole NMN pono.

(9)↗

Punawai Haumana

PubMed Central

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① Hoʻolohi ʻo NMN i ka ʻelemakule

ʻO kekahi o nā uku uku nui o NMN ʻo ia ka mea e hoʻolohi ana i ka kaʻina hana kahiko. ʻO kekahi mau makahiki i hala aku nei, ua hāʻawi ʻo David Sinclair, ka mea noiʻi nui e pili ana i ka Australian Biology a me professor o Genetics, i hōʻike ʻo NAD + e hoʻomoe i ka wā kahiko a me ka hoʻomaka ʻana o nā maʻi pili i ka makahiki. Eia naʻe, ho'ēmi ka hana o NAD + me ka wā'ōpiopio. No laila, i ka wā o ka wā o ka poʻe, nui ka pono no kahi NAD + mua i loko o ko lākou mau kino. ʻO kēia kahi e hele ai ʻo NMN i kahi pāʻani: komo ke NMN i nā pūpuna a hana i ka nui o nā loli kemu ma mua o ka huli ʻana iā NAD + a hoʻohiolo i nā kaʻina hana hoʻokaʻina makahiki.

② Hiki i nā poʻe e ʻeha ana i ka maʻi diabetes ke loaʻa ka pōmaikaʻi mai kāna ʻai ʻana

Ua hoʻokele ʻia kahi hana e noiʻi ai i ke kōkua ʻana o NMN supplementation supplementation i ka mea ʻai a me nā maʻi i pili i nā maʻi i nā kiʻi. Ua hōʻike ʻia ka noiʻi ʻana o ka mau kiole i hāʻawi ʻia i ka waha NMN supplementation i hōʻike i ka nui o ka naʻau i ka insulin a me ka hoʻonui ʻia ʻana o kona mau mea huna. Ua hāʻawi ʻia kēia haʻawina kekahi hōʻike e hiki iā Nicotinamide Mononucleotide a i ʻole hoʻohui NMN supplemental hiki ke kōkua i nā poʻe e loaʻa ana i ka maʻi maʻi.

③ Hoʻohui pū ʻia ʻo NMN Cons konsum me ka Health Heart Hou

Ua aʻo ʻia kekahi ʻano noiʻi e pili ana i ka hoʻopili ʻana o ka NMN supplementation i ka olakino o ka puʻuwai i loko o nā kiʻi Ua hōʻike ʻia ka hōʻike ʻana ʻaʻole ʻo NMN e hoʻohuli wale nō i ke kahe koko a me ka pōʻino o ka i loko o nā kiʻi akā ua alakaʻi ʻia hoʻi i ka kahe koko hou. ʻO ka mea kupanaha loa, ʻo ka ʻiole i hāʻawi ʻia i ka hoʻopihapiha waha NMN, ʻo ka neʻe ʻana o nā moku koko hou ua ʻike ʻia. ʻO ka mea hou aʻe nei, ua loaʻa kekahi noiʻi e noiʻi i nā hopena o NMN ma ke olakino olakino i nā kiʻī a ua hōʻike hou ʻia kēia noiʻi like nā hopena like. Ua hāʻawi aku kēia mau noiʻi i nā hōʻike pono i ka poʻe noiʻi e manaʻoʻiʻo ua hoʻōla ʻo NMN i ka olakino o ka naʻau i loko o nā kanaka.

ʻO Nikotinamide Mononuklepona

Can Hiki i nā poʻe me Alzheimer ke loaʻa ke kōkua mai ka NMN Hoʻohana

I ka poʻe e ʻeha nei i ka maʻi Alzheimer, iho i lalo nā pae NAD. No laila, ke pau ka poʻe e ʻeha ana i ka Alzheimer e hoʻopau iā NMN, hana ke kino i ka hoʻonui ʻana i ka nui o NAD +, a ʻo ia hoʻi, alakaʻi i ka hoʻonui ʻana o ka hoʻokele kaʻa, hoʻonui i ka hana a ka SIRT3, hoʻomaikaʻi i ka hoʻomanaʻo, a hoʻemi i ka neuroinflammation No laila, hiki i nā poʻe e ʻeha nei iā Alzheimer ke loaʻa ka pōmaikaʻi mai ka ʻai ʻana NMN.

⑤ Hoʻomaikaʻi pū kekahi ʻo NMN i nā hana hakuʻala

Hoʻohui ʻia ka supplemental NMN oral me ka hoʻomaʻamaʻa ʻana o nā hana keiki. ʻO kēia no ka mea ke hoʻonui nei ka NMN i ka hana o NAD + a me SIRT1, ka mea i hui pū ʻia me ka hana pūlohi i hoʻonui ʻia.

(10)↗

Punawai Haumana

PubMed Central

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E hele i ke kumu

Ma hea e kūʻai ai i ka pauka Nicotinamide Mononucleotide (NMN) i ka nui?

Inā ʻoe e ʻimi ana e kūʻai i ka pauka Nicotinamide Mononucleotide (NMN) i ka nui, ʻo kahi maikaʻi loa e kūʻai ai i ka pauma NMN ʻo cofttek.com. ʻO Cofttek kahi ʻoihana lāʻau lapaʻau ʻenehana kiʻekiʻe e hoʻolako nei i nā huahana hou a kiʻekiʻe loa mai ka 2008. Ke kaena nei ka hui i kahi hui R&D kupaianaha me nā poʻe i ʻike i ka hoʻomohala ʻana i nā huahana hoʻokūkū. ʻO Cofttek he mau hoa a hoʻolako i kāna huahana i nā ʻoihana lāʻau lapaʻau ma Kina, ʻEulopa, India, a me ʻAmelika Hema. ʻO ka β-Nicotinamide Mononucleotide i hoʻolako ʻia e Cofttek he mea kiʻekiʻe loa a palekana loa no ka ʻai kanaka. ʻO ka mea nui, hoʻolako ka ʻoihana i kēia pauka i ka nui, ʻo ia hoʻi i nā anakahi o 25kgs. Penei, inā ʻoe e ʻimi nei kūʻai i kēia pauka i ka nui, ʻO Cofttek ka hui āu e launa pū ai - ʻo lākou ka Nicotinamide Mononucleotide (NMN) ʻoi aku ka maikaʻi o ka mea hoʻolako i ka mākeke.

Nicotinamide Mononucleotide (NMN) infogram
Nicotinamide Mononucleotide (NMN) infogram
Nicotinamide Mononucleotide (NMN) infogram
Paukū ma:

ʻO Kauka Zeng

Co-hoʻokumu, alakaʻi alakaʻi o ka ʻoihana o ka ʻoihana; Loaʻa ʻo PhD mai ke Kulanui ʻo Fudan i ka kemika kemika. Ma mua o ʻeiwa mau makahiki o ka ʻike i ke kemika kemika a me ka synthesis hoʻolālā lāʻau; ʻaneʻane 10 mau pepa noiʻi i paʻi ʻia i loko o nā puke pai mana, me ʻoi aku o ʻelima mau Sila Nui Kina.

E hoʻomaopopo '

(1). Yao, Z., et al. (2017). Pākuʻi ʻo Nicotinamide Mononucleotide i ka hoʻonā ʻana iā JNK e hoʻohuli i ka maʻi Alzheimer.

(2). Yoshino, J., et al. (2011). ʻO Nicotinamide Mononucleotide, kahi Key NAD (+) waena, mālama i ka Pathophysiology o Diet a me ka maʻi diabetes i loko o nāʻiole. Pūnaewele Metabolism.

(3). Yamamoto, T., et al. (2014). ʻO Nicotinamide Mononucleotide, kahi waena o NAD + Synthesis, pale i ka puʻuwai mai Ischemia a me Reperfusion.

(4). Wang, Y., et al. (2018). Hoʻomaʻamaʻa ʻo NAD + Supplementation i nā hiʻohiʻona Key Alzheimer a me nā pane ʻino DNA ma kahi Model Mouse AD hou me ka hoʻōla DNA hoʻomaikaʻi.

(5). Keisuke, O., et al. (2019). Nā hopena o ka NAD Metabolism i hoʻololi ʻia i nā maʻi Metabolic. Ka Nūpepa o nā ʻEpekema Biomedical.

(6). Huakaʻi e mākaʻikaʻi egt.

(7). Oleoylethanolamide (oea) -ʻo ka wana kupua o kou ola.

(8). Anandamide vs CBD: ʻo wai ka mea ʻoi aku ka maikaʻi no kou olakino? ʻO nā mea āpau āu e ʻike ai e pili ana iā lākou!

(9). ʻO nā mea āpau e pono ai ʻoe e ʻike e pili ana i ka ribotide ribotide nikotinamide.

(10). ʻO nā mea kōkua Magnesium l-threonate: nā pono, nā hana, a me nā hopena ʻaoʻao.

(11). Palmitoylethanolamide (pea): nā pono, nā huahana, nā hoʻohana, nā mea hoʻohui.

(12). ʻO nā pono olakino 6 kiʻekiʻe loa o resveratrol supplement.

(13). ʻO nā pono kiʻekiʻe he 5 o ka lawe ʻana i ka phosphatidylserine (ps).

(14). ʻO 5 keu pono o ka lawe ʻana i ka quyrone pyrroloquinoline (pqq).

(15). ʻO ka waihona nootropic ʻoi loa o ka alpha gpc.

Kauka Zeng Zhaosen

Luna Hoʻokele

Co-hoʻokumu, alakaʻi alakaʻi o ka ʻoihana o ka ʻoihana; Loaʻa ʻo PhD mai ke Kulanui ʻo Fudan i ka kemika kemika. Ma mua o ʻeiwa mau makahiki o ka ʻike i ke kahua synthetic organic o ka chemistry lāʻau. ʻIke waiwai i ka kemika kombinatorial, kemika lāʻau a me ka synthesist custom a me ka hoʻokele papahana.

E kiʻi mai iaʻu i kēia manawa